A Versatile, High-Value Sterilant for the Biopharmaceutical Industry

نویسندگان

  • Barry Wintner
  • Anthony Contino
  • Gary O’Neill
چکیده

LEVEL: INTERMEDIATE L ast month, Part 1 of this article discussed some proven applications of chlorine dioxide (CD) gas and solutions as cleaning/sterilizing agents for isolators, process vessels, filter membranes, water systems, hard surfaces, and cleanrooms. Potential applications were also described, including the production of sterilized water from USP-grade water; sanitization of chromatography columns, resins, and membranes; biowaste kill; and sterilization of disposable process systems. This month, Part 2 discusses economic and validation issues as well as methods of production.

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تاریخ انتشار 2005